I have never heard anything bad about Isuzus other than the fact that the Getrags are just plain better. The fact they generally only used the Isuzus on 4cyl engines, people also assume that they are a weaker trans.
But the biggest factor depends on what your body is, as the Isuzu and Getrag are not interchangeable fully, the shift links and cluch components are different. Most people stick to what they have currently, but when given the choice they pick the Getrags.
PS, I have an easily repairable getrag most likely forsale, pm for details.