Covid... oh, I remember. New protein-based vax's. Different in kind than what's been. (Page 1/1)
rinselberg MAR 07, 03:25 AM
This the latest on Covid vaccines. I think there will be a push for another round of Covid booster shots in 4Q 2022. If Covid cases severe enough to make people seek medical treatment start to kick up again. Which wouldn't surprise me.

New protein-based vaccines are now in the process or just now getting in line for FDA review. These are protein-based vaccines, which are different in kind than the mRNA vaccines from Pfizer and Moderna, and also different in kind from J&J's viral vector vaccine.

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Last week, Sanofi and GSK (GlaxoSmithKline) announced that their [protein-based] COVID-19 vaccine is highly effective—as high as 100% against hospitalization, according to the results of a clinical trial shared by the companies. It's also effective as a booster, and Sanofi and GSK said the vaccine will be submitted to the US Food and Drug Administration as well as European regulators for use as a primary COVID-19 vaccine series and a booster.


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The makers of Novavax, a similar [protein-based] vaccine, submitted data for authorization to the FDA last month. In January, Moderna and Pfizer announced they were working on omicron-specific COVID-19 vaccines. There are also other COVID-19 vaccines in various stages of development around the world.

As Dr. Anthony Fauci alluded to at a press briefing Wednesday, moving forward, public health agencies might put more research efforts towards a universal COVID-19 vaccine that can work against multiple variants, as opposed to focusing on vaccines that are based on earlier strains of the virus. One pan-coronavirus vaccine, developed by scientists with the US Army, is being tested and might have the potential to work against future strains of the coronavirus.


Jessica Rendall for CNET; March 4, 2022.
https://www.cnet.com/health...fi-gsk-what-to-know/

[This message has been edited by rinselberg (edited 03-07-2022).]

rinselberg MAR 07, 04:45 AM
Just for good measure... what immunologists have been pondering and researching since "Covid" became a thing. Enough to boggle any lay person's mind.

"What the Omicron wave is revealing about human immunity"

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Immunologists have raced to work out how to protect against multiple variants of [the] SARS-CoV-2 [virus]. Their research has yielded a wealth of insights and a few surprises.


Cassandra Willyard for Nature; February 2, 2022.
https://www.nature.com/articles/d41586-022-00214-3
rinselberg MAR 07, 05:55 PM
Canada forges ahead with a Covid vaccine for vegans!

"World's First Plant-Based Vaccine For COVID-19 Approved In Canada"

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Canada has become the first country in the world to approve a plant-based vaccine for COVID-19. Delivered by the Quebec-based pharmaceuticals company Medicago, the prophylactic foregoes the need for animal products in manufacturing a vaccine to defend against the SARS-CoV-2 pathogen.

The tobacco plant’s close relative Nicotiana benthamiana is behind the solution, being used as a living factory to churn out virus-like particles. These are able to mimic SARS-CoV-2’s spike protein, effectively acting as a dress rehearsal for the disease so that when the real deal makes an appearance the body is primed to defend itself.

After the plant has cooked up its COVID-19 mimickers, they’re removed from its leaves, purified, and combined with an adjuvant formulated by GlaxoSmithKline to create the injectable treatment.

As well as being a plant-based vaccine, the novel pharmaceutical represents an opportunity to increase COVID-19 shot availability globally as it only needs to be cooled to between 2-8°C (35.6-46.4°F), an easy requirement compared to the extremely cold conditions mRNA vaccines must be stored in to remain viable.

Representing the world’s first plant-based vaccine for COVID-19, the new treatment has been approved for use in adults aged 18 to 64 with an efficacy of 71 percent in preventing COVID-19 infection. However, there are currently insufficient data to approve its use for people aged 65 and older.


That's about half of what's online in this brief writeup.

Rachael Funnell for IFLScience; March 7, 2022.
https://www.iflscience.com/...-approved-in-canada/

[This message has been edited by rinselberg (edited 03-07-2022).]

rinselberg MAR 19, 11:57 AM
"Vaccines remained highly effective at preventing serious illness and death during omicron surge, [new] CDC report says"

Katie Shepherd for the Washington Post; March 18, 2022.
https://www.washingtonpost....ked-against-omicron/

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Although some fully vaccinated and boosted people came down with mild infections during the omicron surge, the study showed that the vaccines — and especially the booster shot — protected most people from the virus’s worst effects.

“Three doses was better than two — this report highlights the value of the third booster dose,” Moss said.


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The CDC study published Friday looked at cases reported at 21 hospitals across 18 states between March 11, 2021, and Jan. 24, which gives insight into vaccine effectiveness against the alpha, delta and omicron variants. The study also focused specifically on how the vaccines fared when omicron was ascendant.



New CDC study:
https://www.cdc.gov/mmwr/vo...s/71/wr/mm7112e1.htm

[This message has been edited by rinselberg (edited 03-19-2022).]

steve308 MAR 19, 12:14 PM
Some here will always doubt the science. Some won't.
williegoat MAR 19, 01:39 PM
This whole Covid thing is like a global mashup of a couple of childhood games, "Mother May I?" and "Simon Says"

"Mother may I... go to the restaurant?"

"Simon says... wear a mask"

With a little bit of "Musical Chairs" thrown in just for spite. Who will be left without a chair, this time around?

How many of you know the origins of "Ring around the Rosie"?

[This message has been edited by williegoat (edited 03-19-2022).]

rinselberg MAR 19, 03:25 PM

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Originally posted by williegoat:
How many of you know the origins of "Ring around the Rosie"?


How many of us? One more than before. I looked it up. Well, I might as well . . .

"The history of a nursery rhyme — Ring around the Rosie", by Jon Schladweiler, Historian of the Arizona Water Pollution Control Federation, in the "History of Sanitary Sewers" online; February 19, 2002.

https://www.sewerhistory.or...ng-around-the-rosie/


Always look to Arizona for the answers.

[This message has been edited by rinselberg (edited 03-19-2022).]

williegoat MAR 19, 03:50 PM

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Originally posted by rinselberg:

Always look to Arizona for the answers.



We 'Zonies are a wise and resourceful bunch.