As IFLYR22 said, the space frames for all Fiero's came from the factory with the hole for the sunroof in the metal substructure. The only difference between a solid roof car and a sunroof car is whether there is a piece of fiberglass over your head or glass so neither one is stronger than the other:

T-Tops on the other hand significantly weaken the car in torsional and lateral rigidity. That means for example that when you turn a corner, the outside front wheel which takes up much of the weight will cause the frame to bend at that corner. The same thing would happen if you started driving up a ramp with only one of the front wheels, the front end of the car will twist more than the back of the car compared to one without the T-Tops.
To explain why, if you imagine a cube made of a wire frame where the bottom wires of the cube represent the rockers and lower cross members of the car, the vertical wires represent the the door posts, A-pillars, and B pillars, and the top wires represent the roof rails, windshield header and the rear roof crossmember, then it's not hard to see why a T-Top is weaker. To make a T-top, you replace the two roof rails with a single new member connecting the middle of the windshield header to the middle of the rear roof cross member. The top corners of the car are no longer supported by three structural members at 90 degrees to each other (effectively triangulating the corner), but rather by only two. In longitudinal bending, where you try to fold the front of the car on top of the rear, it's about the same strength. In lateral bending where you try to fold the car sideways, it's obviously significantly weaker because while the rockers will resist the bending at the bottom, only a single member does so at the top. Finally, in torsional bending where you try to bend the car diagonally, the lack of two roof rails makes a big difference.
So what does it matter if your car bends? The suspension can't do it's job as well keeping the wheels pointed where you want them when the frame is contorting over bumps and in corners. It also means that gaps between body panels have to be a little larger to allow the larger relative movement between them without rubbing.
(edit to add photo)
[This message has been edited by Bloozberry (edited 04-17-2013).]