Been there, done that.
You will have to re-direct the rear header to avoid the axle, and the front header will need a good chunk taken out to clear the alternator. They dump really low, so you will need some tight radius bends and lots of welding. The A/C compresser will cause interference issues and spark plug access is an issue. All in all, my advice is to sell them and save up for some Sanderson CC-90's or get some ram horn manifolds. The ram horns are ugly, but flow better than some headers and will last forever. There are no clearance issues with the manifolds or the Sandersons.
Good luck.
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1986 SE 350 V8
[This message has been edited by tesmith66 (edited 10-27-2004).]